Each person is a unique case. One DUI is bad. We make mistakes. Multiple is even worse. Your friend is tipping the scale against his favor but I suggest he change his lifestyle and be truthful. In the event he does not he should maintain a positive lifestyle, then in couple years he can reapply with greater success than the first time around.
Also, I dont think him having the interlock device permanently would fix anything other than suggest he has greater issues than seen from the surface.