Question about travel while waiting for NBIB

So I’ve been waiting about a year for my interview. My wife is a permanent resident, but not a citizen yet. I have never had a passport or foreign travel. My wife is concerned that her family is in their 90’s back in mexico and she may not get to see them before they pass away. Would it cause issues with my clearances or anything if my wife travels alone to Mexico to visit her family while I wait for my interview and clearance?

No, it wouldn’t cause issues.

It won’t cause any problems with your clearance if you travel with her either . . . It’s not like you are visiting Moscow . . .